Reimagining the infrastructure of cancer care

Transforming possibilities into results

Featured products & solutions

Clinicians, researchers, and regulators rely on FLATIRON HEALTH® technology and evidence to learn faster and power smarter care for every patient.

Achieve your oncology real-world evidence goals faster and more efficiently

Generate robust evidence and insights by partnering with Flatiron's expert team of clinicians, scientists, and health data analysts.

See how
Flatiron Assist

Unleash precision oncology with our customizable clinical decision support platform

Improve the patient experience, streamline operations, and increase revenue with instinctive workflows, up-to-date treatment guidelines, and actionable data.

See how
server render fail/waiting for island-e84377na60ee5R0 (separate island render, inside)
AmerisourceBergen logo which features the company name in black font on a white backgroundThe Cancer Letter Logo which features the company name in black font on a white backgroundLogo for the Community Oncology Alliance: which includes a badge on the left with the acronym COA in the middle with Community Oncology Alliance around it. In the middle and right side of the logo, Community Oncology Alliance is written out in black text with the phrase Innovating and Advocating for Community Cancer Care below itFDA Logo: The letters 'FDA' in bold, uppercase in a black font on a white backgroundThe logo for the National Institutes of Health which has the organizations name at the bottom in black text and above it are the letters NIH in white in front of an illustrative black box representing an arrowThe Lifebit logo which has three circles connected with lines next to the organization name in all lowercaseFriends of Cancer Research logo which has the organization's name in white text on a black backgroundAssociation of Community Cancer Centers logo which has the abbreviation ACCC in front of two horizontal grey lines. The organization's full name is right below ACCCThe logo for the Duke Margolis Center for Health Policy, which has the serif font Duke logo on the left with a thin vertical line separating it from Margolis Center for Health PolicyThe CancerX logo which is a black word mark Cancer with a stylized outline X.The American Oncology Network logo with letters 'AON' in bold, with 'American Oncology Network' written below in smaller font. To the right is a three-pointed emblem, forming a stylized visual elementAmerisourceBergen logo which features the company name in black font on a white backgroundThe Cancer Letter Logo which features the company name in black font on a white backgroundLogo for the Community Oncology Alliance: which includes a badge on the left with the acronym COA in the middle with Community Oncology Alliance around it. In the middle and right side of the logo, Community Oncology Alliance is written out in black text with the phrase Innovating and Advocating for Community Cancer Care below itFDA Logo: The letters 'FDA' in bold, uppercase in a black font on a white backgroundThe logo for the National Institutes of Health which has the organizations name at the bottom in black text and above it are the letters NIH in white in front of an illustrative black box representing an arrowThe Lifebit logo which has three circles connected with lines next to the organization name in all lowercaseFriends of Cancer Research logo which has the organization's name in white text on a black backgroundAssociation of Community Cancer Centers logo which has the abbreviation ACCC in front of two horizontal grey lines. The organization's full name is right below ACCCThe logo for the Duke Margolis Center for Health Policy, which has the serif font Duke logo on the left with a thin vertical line separating it from Margolis Center for Health PolicyThe CancerX logo which is a black word mark Cancer with a stylized outline X.The American Oncology Network logo with letters 'AON' in bold, with 'American Oncology Network' written below in smaller font. To the right is a three-pointed emblem, forming a stylized visual element

New and noteworthy

featured news and insights

Explore the latest insights, research, and stories from Flatiron's global team.

  • New research confirms data quality as the defining priority across the real-world evidence landscape

    As oncology grows more complex and the pace of innovation accelerates, life sciences organizations are placing a premium on high-quality, complete, and scalable real-world data. New insights from two independent surveys confirm that data quality and cohort scale are now prerequisites for confident decision-making and insight generation, especially as the industry evolves from retrospective analysis to predictive and AI-driven applications.

    Read more

  • From innovation to strategic insight: making sense of rapid advances in bladder cancer care

    The bladder cancer landscape is evolving rapidly. The emergence of immune checkpoint inhibitors (ICIs) has fundamentally reshaped treatment, especially for muscle-invasive (MIBC) and advanced disease cases, and antibody-drug conjugates (ADCs) have introduced a new level of precision by targeting proteins like Nectin-4 commonly found on bladder cancer cells. The combination of these novel modalities is now producing much better outcomes — even in the perioperative setting for MIBC patients where chemotherapy used to be the main option, as we recently learned at the 2026 ASCO Genitourinary Cancers Symposium in San Francisco.

    Read more

  • The real-world perspective: Why global RWE matters in modern oncology

    In my work as a clinician, I've spent nearly two decades watching the same pattern repeat itself: the treatments that earn approval through randomised controlled trials, our gold standard for evidence, are often tested on populations that don't look like the patients sitting in my clinic. The gap between what clinical trials demonstrate and what I observe in clinical practice isn't merely theoretical—it's reflected in patients sitting in our clinics—and this is precisely where real-world evidence becomes not just valuable but essential.

    Read more
View more resources